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AS06-148

 

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Product sheet »

 

Product description

 

Background
LRIG1 protein is coded by a gene on a chromosome band 3p14.3, this region is known to be deleted in various human cancers. LRIG1 is considered to be a a tumour suppressor gene in humans. LRIG1 is an integral cell-surface membrane protein that is expressed by specific cells in various human tissues and that its 143-kDa form might be cleaved into 111-kDa and 32-kDa fragments.
The LRIG1 protein may inhibit the growth of tumors of glial cells and the down-regulation of the LRIG1 gene may be involved in the development and progression of the tumor.

Quantity: 100 ug

Immunogen:  synthetic peptide conjugated to KLH.  The peptide corresponded to part of the cytoplasmic tail (C-terminal part).

Type of antibody: polyclonal

Antibody format: affinity purified rabbit IgG, lyophilized

Tested applications:  Western Blot working concentration - 1 microgram/ml.              Immunohistochemistry: 0.5 - 1 microgram/ml.Staining has been one on normal human tissues,  in epithelia in various organs, scattered neurons, and muscles.

Related product: hen anti-LRIG1 antibody (AS06 156)

Reference: Nilsson et al. (2003) LRIG1 protein in human cells and tissues. Cell and Tissue Research 312: 65.

ANTIBODIES ARE FOR RESEARCH PURPOSE ONLY

 

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Last modified: 05/29/09