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Brevetoxin B

 

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Clonagen

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Brevetoxin B (pbTx-2) Cat. No. AF0100


Description
A polycyclic polyether, isolated from marine dinoflagellate Karenia
breve (Ptychodiscus brevis, or Gymnodinium breve in earlier literatures)
is one of the toxins responsible for the ‘red tide’ massive fish kills. This
compound forms a ladder-like-arranged multiple ring structure with an
unusual acrolein side-chain on one of the terminal rings. Together with
other congeners, they are known to disrupt neurotransmission by
opening sodium channels.

Form
Ivory crystal solid


Molecular weight
894

Molecular formula
C50H70O14

Structure


Purity
98% by HPLC

Solubility
MeOH, EtOH or DMSO

Storage
Stable in -25 oC for 2 years

Toxicity
LD50: 0.15~0.27 mg/kg ip. to mice

Reference
Lewis, R. J., Toxicon 30, 207 (1992)
Gawley, R. E., et al., Toxicon 30, 780 (1992)

1. Harmonized tariff code: 2932.29.5050.
2. This product does not contain any animal derived additives, such as albumin.
3. This product is for laboratory use only, not for human or drug use.
 

 

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Last modified: 05/29/09