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Cultrex 3D Culture 96 Well BME Cell Proliferation Assay

 

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Cultrex® 3D Culture 96 Well BME Cell Proliferation Assay


Recent studies indicate that the composition of the extracellular environment influences cellular responses to apoptosis inducing agents1, 2 implicating a role for extracellular proteins in influencing both toxicity and drug resistance. As a result, this environment must be mimicked during the course of cell-based studies to provide the most accurate translation to animal models The Cultrex® 3-D Culture Cell Proliferation Assays provide a more physiologically relevant assessment when using cell models in the screening process for compounds that influence toxicity. These assays offer a flexible, standardized, high-throughput format for quantitating the degree to which pharmacological compounds influence toxicity or tumorigenicity within in vivo-like environments. The Cultrex® 3-D Culture Cell Proliferation Assay has been adapted to multiple formats so that cell proliferation may be evaluated within different extracellular matrices; BME, Laminin I, and Collagen I.

 

Applications:

tests for the inhibition of proliferation and formation of 3D structures in a BME matrix

 

Components:

Part #

Component

Size

 

3445-005-01

3-D Culture Matrix

5 ml

 

3445-096-02

Cell Proliferation Reagent

3 ml

 

3445-096-03

3D Culture Stripwells 96 well

2 plates

 

Storage:

Components are stored at -20şC and at room temperature.

 

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Last modified: 05/29/09