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Okadaic acid

 

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Okadaic acid (OA) Cat. No. AE0100


Description
An ionophore-like polyether isolated from marine dinoflagellate
Prorocentrum lima. Implicated as causative agent of diarrhetic
shellfish poisoning. Potent inhibitor of protein phosphatase type 1
(PP1) and protein phosphatase type 2A (PP2A). Useful for the
study of protein phosphatases in cell extracts as well as intact
cells.

Form
White crystal solid

Molecular weight
804.5

Molecular formula
C44H68O13

Structure

 

 


Purity
95% by HPLC

Solubility
MeOH, EtOH or DMSO

Storage
Stable in -25 oC for 2 years

Toxicity
LD50: 200 g/kg for mice, IP

Reference Yasumoto, T., et al. 1985. Tetrahedron 41, 1019.
Cohen, P. 1989. Ann. Rev. Biochem. 58, 453.

1. Harmonized tariff code: 2932.29.5050.
2. This product does not contain any animal derived additives, such as albumin.
3. This product is for laboratory use only, not for human or drug use.
 

 

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Last modified: 05/29/09