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Okadaic acid (OA) Cat. No. AE0100
Description
An ionophore-like polyether isolated from marine dinoflagellate
Prorocentrum lima. Implicated as causative agent of diarrhetic
shellfish poisoning. Potent inhibitor of protein phosphatase type 1
(PP1) and protein phosphatase type 2A (PP2A). Useful for the
study of protein phosphatases in cell extracts as well as intact
cells.
Form
White crystal solid
Molecular weight
804.5
Molecular formula
C44H68O13
Structure
Purity
95% by HPLC
Solubility
MeOH, EtOH or DMSO
Storage
Stable in -25 oC for 2 years
Toxicity
LD50: 200 g/kg for mice, IP
Reference Yasumoto, T., et al. 1985. Tetrahedron 41, 1019.
Cohen, P. 1989. Ann. Rev. Biochem. 58, 453.
1. Harmonized tariff code: 2932.29.5050.
2. This product does not contain any animal derived additives, such as albumin.
3. This product is for laboratory use only, not for human or drug use.
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