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Product Launch
Osteopontin (rodent) EIA Kit
Assay Designs™ is happy to announce the launch of a ready-to-use enzyme
immunoassay kit for the measurement of Osteopontin culture supernates, EDTA
plasma, and urine samples from mouse and rat origins.
Assay
Performance Specifications |
Catalog
Number |
900-090A |
Standard
Range |
3.13 – 100 ng/mL |
Sensitivity |
3.03 ng/mL |
Sample Types |
culture
supernates, EDTA plasma, and urine |
Number of
Samples |
40 in
duplicate |
Time to
Answer |
3 hours |
Species
Reactivity |
mouse & rat |
Size |
1 x 96 well |
Osteopontin
(OPN) is an acidic extracellular matrix cell adhesion protein that is relatively
abundant not only in bone matrix, plasma, urine, and milk, but is also found in
malignant and atherogenic tissues. Phosphorylation, glycosylation and calcium
modifications allow intact and fragmented Osteopontin to direct a variety of
diverse responses including tissue remodeling, inflammation and cell survival.
Plasma Osteopontin has been shown to be a positive indicator of colon and lung
cancers as well as metastatic carcinomas. The notable presence of Osteopontin in
a variety of tumors is strongly correlated to pathological stage, suggesting its
critical role in tumor invasiveness, progression and metastasis. In addition,
Osteopontin inhibits inducible nitric oxide synthase activity, thereby
protecting tumor cells from NO-mediated macrophage cytotoxic attack. Osteopontin
is found in atherosclerotic plaques and may drive a number of diabetic vascular
pathologies.
Product Features & Benefits
-
Accurate
–
parallelism data demonstrates the recombinant standard accurately reflects
natural osteopontin
-
Fast
–
results from up to 40 samples in duplicate in just 3 hours
-
Easy-to-use –
color-coded reagents reduce error
-
Convenient
– ready-to-use reagents and pre-coated 96-well plate
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