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Hsp70 High
Sensitivity EIA Kit
A
ready-to-use enzyme immunoassay kit for the measurement of inducible Hsp70
(Hsp72) in serum and plasma samples.
Assay Performance
Specifications |
Catalog Number |
EKS-715 |
Standard Range |
0.20 – 12.5 ng/mL |
Sensitivity |
90
pg/mL |
Sample Types |
Serum and EDTA plasma |
Number of Samples |
39
in duplicate |
Time to Answer |
4.5
hours |
Species Reactivity |
Human, mouse, rat |
Size |
1 x
96 well |
Hsp70 is a molecular chaperone
whose expression is induced upon exposure of the cell or organism to conditions
of stress. It prevents protein aggregation and promotes the refolding of
proteins that become damaged in response to environmental insults, pathogens,
and disease. Its activity is essential for cellular survival and recovery under
stress conditions, as well as for the maintenance of normal cellular function
under non-stress conditions. Hsp70 has been implicated to play a role in a
variety of disease and physiological processes such as hyperthermia,
hypertension, toxic exposure to chemical agents, hypoxia, ischemia,
inflammation, autoimmunity, apoptosis, cancer, organ transplantation, and
bacterial and viral infections. Hsp70 is a key regulator of many normal
physiological processes including aging, spermatogenesis, menstruation, and
physical activity such as exercise. Assay Designs Hsp70 High Sensitivity EIA
kit is designed to evaluate and monitor Hsp70 as a research tool in these
processes, providing a key to understand of the role of Hsp70 in physiology and
disease.
Product
Features & Benefits
-
Sample types-
only commercially available ELISA for the analysis of serum and plasma Hsp70
-
Sensitive-
measure as little as 90 pg/mL of Hsp70
-
Specific-
low reactivity with other Hsp70 family members
such as
Hsc70 (Hsp73), Grp78, DnaK (E. coli), or Hsp71 (M. tuberculosis)
-
Validated-
stressed and non-stressed
serum and plasma samples evaluated in the assay
-
Quantitative-
fully quantitative results surpass semi-quantitative Western blot analysis
-
Convenient-
ready-to-use liquid color coded reagents and pre-coated 96-well plate
-
Time Saving-
results from up to 39 samples in duplicate in just 4.5 hours
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