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Product sheet »

 

Product description

 

Background
Mammaglobin is a 93 amino acids peptide belonging to the secretoglobin superfamily. Mammaglobin is expressed by normal breast and skin tissues and is over-expressed in many human breast cancer tumours. In breast tissue, mammaglobin is expressed as a secreted heterodimer together with the other secretoglobin member lipophilin B.

Quantity: 100 ug

Related product: Blocking peptide for anti-mammaglobin antibodies (AS03 029S)

Immunogen: a 16 amino acids peptide corresponding to the C-terminus of mammaglobin, coupled to a carrier protein (KLH).

Type of antibody: polyclonal

Antibody format: affinity purified rabbit IgG, lyophilized

Cross-reactivity:  No cross-reactivity to lipophilin A, lipophilin B (BU101), lipophilin C (lacryglobin, mammaglobin B), or uteroglobin (Clara cell protein, Clara cell 10 kDa protein) by Western blot analysis of bacterially produced recombinant proteins. Western blot analysis of human breast cancer cells MDA-MB-415 reveals only the mammaglobin band, of approximately 15 kDa. Analysis of other cells and tissues might, however, upon prolonged exposure, reveal additional bands at
higher molecular weight.

Tested applications:  Western Blot (working dilution/conc. 1 microgram/ml);  immunohistochemistry (1 microgram/ml)
 
References:  Sjödin et al. Journal of Investigative Dermatology (2003) 121(2): 428-429.

ALL ANTIBODIES ARE FOR RESEARCH PURPOSE ONLY

 

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Last modified: 05/29/09