Mammaglobin is a 93 amino acids peptide belonging to the secretoglobin
superfamily. Mammaglobin is expressed by normal breast and skin tissues
and is over-expressed in many human breast cancer tumours. In breast
tissue, mammaglobin is expressed as a secreted heterodimer together with
the other secretoglobin member lipophilin B.
Blocking peptide for anti-mammaglobin antibodies (AS03 029S)
a 16 amino acids peptide corresponding to the C-terminus of
mammaglobin, coupled to a carrier protein (KLH).
Type of antibody:
affinity purified rabbit IgG, lyophilized
No cross-reactivity to lipophilin A, lipophilin B (BU101),
lipophilin C (lacryglobin, mammaglobin B), or uteroglobin (Clara cell
protein, Clara cell 10 kDa protein) by Western blot analysis of
bacterially produced recombinant proteins. Western blot analysis of
human breast cancer cells MDA-MB-415 reveals only the mammaglobin band,
of approximately 15 kDa. Analysis of other cells and tissues might,
however, upon prolonged exposure, reveal additional bands at
higher molecular weight.
applications: Western Blot (working dilution/conc. 1 microgram/ml);
immunohistochemistry (1 microgram/ml)
Sjödin et al. Journal of Investigative Dermatology (2003) 121(2):
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